Patients at a greater risk for transfusion-associated graft versus host disease (TA-GVHD)include all the following except
A)Fetuses
B)Older adults
C)Patients with Hodgkin's disease
D)Hematopoietic stem cell transplant recipients

Question

Quizplus · Accepted Answer

Transfusion-associated graft versus host disease (TA-GVHD) is a rare but often fatal complication of blood transfusion. It occurs when immunocompetent T cells in the transfused blood product engraft in the recipient, recognize the host tissues as foreign, and initiate an immune response against the host. Patients at greater risk for TA-GVHD include those with compromised immune systems, such as fetuses (who have not fully developed their immune systems), patients with Hodgkin's disease (who often have compromised immunity due to the disease itself or its treatment), and hematopoietic stem cell transplant recipients (who are immunosuppressed to prevent rejection of the transplant). Older adults, while they may have a somewhat diminished immune system compared to younger adults, are not specifically at a higher risk for TA-GVHD compared to the general population without other underlying conditions.

Patients at a Greater Risk for Transfusion-Associated Graft Versus Host