All of the following statements are true about transfusion-related immunomodulation (TRIM)except
A)Cause remains unproven.
B)First recognized in liver transplant recipients.
C)Possible deleterious effects include increased recurrence of cancer.
D)Refers to immune suppression following transfusion of allogeneic blood products.

Question

Quizplus · Accepted Answer

Transfusion-related immunomodulation (TRIM) was not first recognized in liver transplant recipients; it was observed in the context of kidney transplantation. TRIM refers to the immune suppression and other immune alterations following transfusion of allogeneic blood products, and its exact cause remains unproven. It has been associated with possible deleterious effects, including an increased recurrence of cancer.

All of the Following Statements Are True About Transfusion-Related Immunomodulation