A 55 year old male presents with a history of chronic dyspepsia and with recent weight loss. Investigation by gastroscopy reveals a reduction in specialised gastric glands and the presence of slender giemsa staining filaments on the mucosal surface. In addition a gastric mass is seen. This is composed of large B lymphocytes which are negative for cyclin D1 and BCL2. Monoclonality is identified.
A)Gastric DLBCL
B)Anaplastic large cell lymphoma
C)Maltoma
D)Reactive lymphoid proliferation
E)T-cell lymphoma.

Question

Quizplus · Accepted Answer

The gastric mass is composed of large B lymphocytes, which is characteristic of Diffuse Large B-Cell Lymphoma (DLBCL). The negative staining for cyclin D1 and BCL2 helps differentiate it from other lymphomas.

A 55 Year Old Male Presents with a History of Chronic