A 43-year-old man with severe acquired aplastic anemia has not responded to immunosuppressive agents. He remains neutropenic and transfusion-dependent for platelets and red cells. He has an HLA-identical brother who has been cleared as a donor for his planned allogeneic stem cell transplant.They are both cytomegalovirus-seronegative. Which of the following would be prevented by using irradiated cellular blood products for this patient?
A)Cytomegalovirus disease
B)Alloimmunization
C)Transfusion-related graft-versus-host disease
D)Febrile nonhemolytic transfusion reaction
E)Hemolytic transfusion reaction

Question

Quizplus · Accepted Answer

Transfusion-related graft-versus-host disease (GVHD) is prevented by using irradiated cellular blood products. This process inactivates the lymphocytes in the blood product, preventing them from mounting an immune response against the recipient's tissues.

A 43-Year-Old Man with Severe Acquired Aplastic Anemia Has Not