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A 72-Year-Old Man Is Evaluated Because of Back Pain and Fatigue

Question 17

Multiple Choice

A 72-year-old man is evaluated because of back pain and fatigue. Laboratory values indicate he is anemic, with normal leukocyte count and platelet count. He has mild hypercalcemia and a normal serum creatinine level. His gamma globulins are elevated, and serum protein electrophoresis shows the presence of a monoclonal protein, an IgG- K light chain containing immunoglobulin at 4.4 g/dL. His bone marrow contains 20% plasma cells. A skeletal survey reveals multiple osteolytic lesions in the spine, ribs, and skull. Therapy with melphalan and prednisone is initiated. Which of the following agents would NOT be routinely used in his management?


A) Erythropoietin
B) Radiation therapy
C) Intravenous gamma globulin
D) Adequate analgesia (including narcotics, if necessary)
E) A bisphosphonate

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