During evaluation of tumor biopsy specimens, which of the following markers can be used as a histochemical indicator of cell proliferation?
A)Ki-67
B)TP53
C)c-myc
D)Nuclear/cytoplasmic ratio

Question

Quizplus · Accepted Answer

Ki-67 is a nuclear protein that is associated with cellular proliferation. It is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent in resting cells (G0), making it a useful marker for determining the growth fraction of a given cell population.

During Evaluation of Tumor Biopsy Specimens, Which of the Following