The critical tissue for producing a vasodilatory effect of acetylcholine in Robert Furchgott's experiments with rabbit aortas was the

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The critical tissue for producing a vasodilatory effect of acetylcholine in Robert Furchgott's experiments with rabbit aortas was the endothelium. Furchgott discovered that acetylcholine's ability to induce vasodilation was dependent on the presence of the endothelium, a layer of cells lining the blood vessels. This finding was crucial in understanding the role of the endothelium in vascular function and led to the discovery of endothelium-derived relaxing factor (later identified as nitric oxide).

The Critical Tissue for Producing a Vasodilatory Effect of Acetylcholine