A client diagnosed with bipolar disorder is prescribed lithium. The nurse is reviewing the client's medication history for drugs that could interact with lithium. The nurse would monitor the client's serum lithium concentrations closely for toxicity if the client's history included use of which medication? Select all that apply.

Question

Quizplus · Accepted Answer

Medications such as captopril, fluoxetine, and hydrochlorothiazide increase serum lithium concentration, placing the client at increased risk for lithium toxicity. Mannitol and isosorbide increase renal excretion of lithium, thus decreasing lithium concentration.

A Client Diagnosed with Bipolar Disorder Is Prescribed Lithium