PKG and PKA are similar in that both
I. are activated by a cyclic nucleotide monophosphate
II. have nucleotide-binding and kinase domains
III. release their catalytic subunits when activated
IV. phosphorylate downstream proteins to effect cellular change

Question

Quizplus · Accepted Answer

PKG and PKA are similar in that both are activated by a cyclic nucleotide monophosphate (PKG by cGMP and PKA by cAMP), both have nucleotide-binding and kinase domains, and both phosphorylate downstream proteins to effect cellular change. However, not all of them release their catalytic subunits when activated in the same manner, making option III not universally applicable to both.

PKG and PKA Are Similar in That Both