Which of the following is considered a significant problem with using biomarkers of bone turnover in the management of patients with osteoporosis in a clinical setting?
A) They can be repeated over short time intervals thus providing quick results.
B) They are noninvasive.
C) They require no special patient preparation.
D) The measurements are affected by several preanalytical variables both controllable and uncontrollable.

Question

Quizplus · Accepted Answer

Biomarkers of bone turnover are sensitive to a variety of preanalytical variables, including circadian rhythm, food intake, and physical activity, making their measurements potentially inconsistent and challenging to interpret accurately in a clinical setting.

Which of the Following Is Considered a Significant Problem with Using