To receive a diagnosis of substance use disorder, an individual must satisfy at least two diagnostic criteria, one of which has to be a symptom of physical dependence (tolerance or withdrawal).

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The diagnosis of substance use disorder is based on a set of criteria that includes impaired control, social impairment, risky use, and pharmacological criteria (tolerance and withdrawal), but not all criteria must be met for a diagnosis, and physical dependence is not a requirement.

To Receive a Diagnosis of Substance Use Disorder, an Individual