What would be the outcome if the procedure used to make gene-targeted (knock-out) mice was altered in the following ways (consider each situation separately).
(a) The embryo-derived stem (ES) cells did not possess a gene responsible for visible phenotypic trait (such as agouti coat color) that differed from that of the cell in the recipient blastocyst.
(b) The inserted "disrupting" gene (e.g. neo^R) did not insert into the gene of interest.
(c) Chemical transfection or electroporation failed.
(d) The gene knock-out was embryonic lethal

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The Answer of What would be the outcome if the procedure used to make gene-targeted (knock-out) mice was altered in the following ways (consider each situation separately). (a) The embryo-derived stem (ES) cells did not possess a gene responsible for visible phenotypic trait (such as agouti coat color) that differed from that of the cell in the recipient blastocyst. (b) The inserted "disrupting" gene (e.g. neo^R) did not insert into the gene of interest. (c) Chemical transfection or electroporation failed. (d) The gene knock-out was embryonic lethal

What Would Be the Outcome If the Procedure Used to Make