When the translation initiation factor eIF2 is phosphorylated in response to a sudden temperature increase or viral infection, translation can be greatly inhibited. In this case, phosphorylated eIF2 is under _______________ control, and the phosphorylation of eIF2 leads to global (general or widespread) _____________ control.

Question

Quizplus · Accepted Answer

The phosphorylation of eIF2 is a post-translational modification that affects its function in initiating translation. Thus, it is under post-translational control. The consequence of this modification is a global or widespread reduction in translational activity, affecting the synthesis of proteins at the translational level.

When the Translation Initiation Factor EIF2 Is Phosphorylated in Response