A 5-year-old-child, weight 14 kg, with septic shock. Order: dobutamine 10 mcg/kg/min at 2.1 mL/hr; titrate to keep SBP > 90. Dilute as follows: dobutamine 200 mg in D₅W to make a total volume of 50 mL for a syringe pump. Pediatric dosage: 2 to 20 mcg/kg/min. Drug available: dobutamine 250 mg/20 mL
a. What is the concentration per hour?
b. What is the mL per hour?

Question

Quizplus · Accepted Answer

The Answer is a. 14 kg x 10 mcg/kg/min = 140 mcg/min, 140 mcg/min x 60 min/hr = 8400 mcg/hr
b. 200 mg = 200,000 mcg
200,000 mcg: 50 mL = x mcg: 1 mL
50x = 200,000
x = 4000 mcg/mL concentration

a. 14 kg x 10 mcg/kg/min = 140 mcg/min, 140 mcg/min x 60 min/hr = 8400 mcg/hr b. 200 mg = 200,000 mcg 200,000 mcg: 50 mL = x mcg: 1 mL 50x = 200,000 x = 4000 mcg/mL concentration

A 5-Year-Old-Child, Weight 14 Kg, with Septic Shock