Chloe O'Brien, born in England in April 1992, was the first baby to be born after in vitro fertilization following DNA analysis before implantation. Her parents were carriers of the cystic fibrosis gene. Chloe's mother:

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Chloe O'Brien's birth marked the first use of preimplantation genetic diagnosis (PGD), where DNA analysis is done before implantation to ensure the baby does not inherit specific genetic conditions. This process allowed her parents to know she did not have cystic fibrosis before she was even implanted in her mother's womb, eliminating the need for procedures like amniocentesis or chorionic villus sampling to test for the disease after pregnancy had begun.

Chloe O'Brien, Born in England in April 1992, Was the First