Given that a normal albumin is approximately 40 g/L, a normal glucose is approximately 900 mg/L, and a normal BUN is approximately 100 mg/L, why is albumin (which has a much higher concentration) not considered in the equation to estimate osmolality?

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Quizplus · Accepted Answer

Osmolality is a measure of the number of particles in a solution, not the concentration.The approximate normal level for albumin is 40g/L, which is equivalent to 0.62 mmol/L.Glucose, on the other hand, has an approximate normal level of 900 mg/L, which is equivalent to 5 mmol/L.Thus when it comes to the number of moles of albumin present, albumin does not contribute significantly to osmolality and is not included in the equation.

Given That a Normal Albumin Is Approximately 40 G/L, a Normal