Which of the following syndromes has a mutation in the upstream promoter region of the gene for UDP-glucuronyl transferase 1 (UGT1) and results in reduced production of the enzyme?

Question

Quizplus · Accepted Answer

Individuals with Gilbert's syndrome have a mutation in the upstream promoter region of the gene for UDP-glucuronyl transferase 1 (UGT1) that inserts an extra TA sequence into the TATA box region of the gene, resulting in reduced production of the enzyme.

Which of the Following Syndromes Has a Mutation in the Upstream