Within the Hepatocyte's Cytoplasm, There Is Normally More AST Than

Within the hepatocyte's cytoplasm, there is normally more AST than ALT by a factor of about ______; however, the amount of cytoplasmic ALT ______ with alcohol abuse, pyridoxine deficiency, and in cirrhosis, which ______ the cellular ratio of AST to ALT.

A) 1.2, decreases, increases
B) 1.5, increases, decreases
C) 1.5, decreases, increases
D) 1.2, increases, decreases