If a Protein Is Supposed to Consist of the Amino

If a protein is supposed to consist of the amino acid sequence valine-valine-histidine and instead it consists of the sequence alanine-valine-histidine, most likely

A) there has been a point mutation in the first codon.
B) there has been a point mutation at the eighth base pair.
C) the change will not be noticed.
D) this is a gross mutation; the organism will not survive.