A change of information from normal hemoglobin to sickle hemoglobin is a

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A point mutation refers to a change in a single nucleotide base in the DNA sequence. Sickle cell anemia is caused by a point mutation in the beta-globin gene, where the amino acid glutamic acid is replaced by valine at the sixth position of the beta-globin chain. This results in hemoglobin molecules that can form stiff rods within red blood cells, causing them to take on a sickle shape.

A Change of Information from Normal Hemoglobin to Sickle Hemoglobin