Which of the following statements are true of steroid hormones?
1)They interact with their target cells by binding to specific receptors located in both the intracellular cytoplasmic and nuclear fractions of the cells.
2)They enter the cell primarily through diffusion.
3)Transport proteins are necessary to carry steroids from the organ of synthesis, through the blood stream, to their site of action.
4)They utilize the second messenger signaling system.

Question

Quizplus · Accepted Answer

The transport and actions of steroid hormones are based on the high lipid solubility and low water solubility characteristics of these substances.Because of their low water solubility, transport proteins are necessary to carry steroids from the organ of synthesis, through the highly polar nature of the blood stream, to their site of action.Once at the site of action, steroids enter the cell primarily through diffusion, bind to the receptor molecule, and produce a conformational change in the receptor structure.These intracellular receptors are located in both the cytoplasmic and nuclear fractions of the cells.

Which of the Following Statements Are True of Steroid Hormones