An elevated serum insulin-like growth factor 1 (IGF-1) is useful in the diagnosis of which disease?

Question

Quizplus · Accepted Answer

A growth hormone excess is associated with acromegaly.The major effect of growth hormone is to induce the synthesis of an insulin-like growth factor (IGF-1) by the liver.In patients with acromegaly, IGF-1 levels are raised to a greater extent than those of growth hormone itself.The recent availability of commercial immunoassays for IGF-1 has allowed for the routine measurement of this circulating growth factor for the diagnosis and management of patients with acromegaly.

An Elevated Serum Insulin-Like Growth Factor 1 (IGF-1) Is Useful