Select the correct sequence of steps that must occur for the development of colorectal cancer.
1)Mutations of tumor suppressor gene 53 and deletions on chromosome 18q coincide with transition to malignancy.
2)Mutations in the adenomatous polyposis coli (AOC) tumor-suppressor gene occur early in the development of polyps.
3)Oncogenic K-ras mutations arise during the adenomatous stage.

Question

Quizplus · Accepted Answer

The following sequential steps must occur for the development of colorectal cancer: mutations in the adenomatous polyposis coli (AOC) tumor-suppressor gene occur early in the development of polyps; oncogenic K-ras mutations arise during the adenomatous stage; mutations of tumor suppressor gene 53 and deletions on chromosome 18q coincide with transition to malignancy.

Select the Correct Sequence of Steps That Must Occur for the Development