An increase in contractility is demonstrated on a Frank-Starling diagram by

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[IV D 5 a]. An increase in contractility produces an increase in cardiac output for a given end-diastolic volume, or pressure. The Frank-Starling relationship demonstrates the matching of cardiac output (what leaves the heart) with venous return (what returns to the heart). An increase in contractility (positive inotropic effect) will shift the curve upward.

An Increase in Contractility Is Demonstrated on a Frank-Starling Diagram