According to the Cross-Linkage Theory of Aging,bonds Between Protein Fibers

According to the cross-linkage theory of aging,bonds between protein fibers in connective tissue can lead to __________.

A) tightening of the skin and strengthening of the kidneys
B) loss of flexibility in the skin and clogging of arteries
C) increased flexibility and strengthening of the bones
D) reduced production of many hormones, especially estrogen