The outside of a neuron is positively charged at resting potential. Why do K+ ions leave the cell when K+ channels open during an action potential?
A) The diffusion gradient is the only factor that affects ion movement.
B) K+ ions are actively pumped out by the sodium-potassium pump acting in reverse.
C) Voltage-gated K+ channels open when membrane potential reaches +50 mV during the depolarization phase. The diffusion gradient and electrical force cooperate to drive K+ ions out of the cell.
D) Negatively charged proteins leave the cell at the onset of the action potential.
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