Botulinum Toxin-- a Toxin Produced by the Bacterium Clostridium Botulinum

Botulinum toxin-- A toxin produced by the bacterium Clostridium botulinum. Known for sometimes lethal poisoning from infected meat products. In modern controlled medical or cosmetic use, the very same toxin is known as Botox.
Tetanus toxin-- Another very potent neurotoxin produced by Clostridium tetani.
Strichnine-- A highly poisonous alkaloid produced by the Strychnos nux-vomica tree, historically used to kill rats and other pests.
-Botulinum toxin, or "botox", has become popular for cosmetic surgery. The toxin prevents neurosecretory vesicles from docking at the plasma membrane and releasing neurotransmitter. How would this toxin affect the neuromuscular junction?

A) Since ACh is not released, the muscles stay in a state of repeated contraction.
B) Since ACh is not released, the muscles are not activated to contract and remain relaxed.
C) Buildup of ACh causes promiscuous activation of all nearby sensory neurons.
D) Buildup of ACh leaks back into the brain, creating a calming effect.