Bartel's research group showed that an RNA replicase ribozyme could be created by

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Bartel's research group used a method known as in vitro evolution to create an RNA replicase ribozyme. This method involves starting with random components and allowing natural selection to evolve molecules that are better and better at a specific function, in this case, replicating RNA. The researchers added a mixture of nucleotides and other necessary components to a test tube and allowed the molecules to interact and replicate. The resulting replicase ribozyme was able to catalyze the replication of RNA molecules, demonstrating that functional RNA molecules could be evolved using this approach.

Bartel's Research Group Showed That an RNA Replicase Ribozyme Could