Insulin is a hormone produced by the pancreas.When insulin binds to its receptor,which of the following will occur?
A)A G-protein will change its conformation to the "on" position thereby allowing the effector to be activated.
B)The G-protein will become active when GTP is replaced by GDP.
C)A receptor tyrosine kinase will change its conformation (i.e.form a dimer)thereby allowing phosphorylation to occur.
D)A receptor tyrosine kinase will dissociate into two monomers thereby allowing phosphorylation to occur.

Question

Quizplus · Accepted Answer

Insulin binds to a receptor tyrosine kinase, which causes a conformational change and allows for the formation of a dimer, leading to phosphorylation and downstream signaling. Choice A is incorrect because insulin does not activate G-proteins. Choice B is incorrect because G-proteins are not involved in insulin signaling. Choice D is incorrect because the receptor does not dissociate into monomers, but rather forms a dimer.

Insulin Is a Hormone Produced by the Pancreas