The negative symptoms of schizophrenia seem to be associated with loss of brain tissue, which implies the presence of some sort of neurological problem.

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Negative symptoms of schizophrenia, such as lack of motivation, social withdrawal, and diminished emotional expression, have been linked to structural brain abnormalities, including loss of brain tissue, suggesting an underlying neurological component to the disorder.

The Negative Symptoms of Schizophrenia Seem to Be Associated with Loss