Forward genetics begins with a phenotype and detects and analyzes the genotype that causes the phenotype. Reverse genetics begins with a gene sequence and, through analysis, determines the phenotype that it encodes. Particular mutations can be introduced at specific sites within a gene by means of site-directed and oligonucleotide-directed mutagenesis.
-A geneticist interested in immune function induces random mutations in a number of specific genes in mice and then determines which of the resulting mutant mice have impaired immune function. This procedure is an example of
A) forward genetics.
B) reverse genetics.
C) both forward and reverse genetics.
D) neither forward nor reverse genetics.

Question

Quizplus · Accepted Answer

The procedure described involves starting with specific gene sequences, inducing mutations, and then observing the resulting phenotypes, which is characteristic of reverse genetics.

Forward Genetics Begins with a Phenotype and Detects and Analyzes