Natural selection changes allelic frequencies; the direction and magnitude of change depend on the intensity of selection, the dominance relations of the alleles, and the allelic frequencies. Directional selection favors one allele over another and eventually leads to fixation of the favored allele. Overdominance leads to a stable equilibrium with maintenance of both alleles in the population. Underdominance produces an unstable equilibrium because the heterozygote has lower fitness than those of the two homozygotes.
-How does overdominance differ from directional selection?
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