If a series of drug resistance genes are transferred together routinely, what is the most likely method of transfer?

Question

Quizplus · Accepted Answer

Genes for drug resistance may reside individually on the bacterial chromosome or on plasmids. Clusters of multiple drug resistance genes are occasionally on chromosomes but are more commonly on plasmids. Also, in general, plasmid DNA is entirely transferred in a conjugal cross of $F^+$ cells with $F^-$ cells. R-factors are like those $F^+$ cells with just a few extra, closely linked drug resistance genes. So the conjugal transfer of an R-factor is the process that is most likely to transfer multiple drug resistance.

If a Series of Drug Resistance Genes Are Transferred Together