A 4-year-old boy has a yearlong history of repeated staphylococcal and streptococcal infections. He was referred to the genetic counseling unit where he was found to have depressed superoxide dismutase activity. Treatment with which of the following is most likely to be successful?

Question

Quizplus · Accepted Answer

Repeated infections with depressed superoxide activity characterize chronic granulomatous disease. Interferon-$\gamma$ has been successful in treatment. Loss of adenine deaminase is the lesion found in SCID patients. $TGF-\beta$ inhibits T-cell and B-cell proliferation.

A 4-Year-Old Boy Has a Yearlong History of Repeated Staphylococcal CD4+CD4^+CD4+

A 4-Year-Old Boy Has a Yearlong History of Repeated Staphylococcal $CD4^+$