An increase in the level of glucose 6-phosphate is expected to have which of the following effects on carbohydrate metabolism in hepatocytes?

Question

Quizplus · Accepted Answer

Both covalent modification and allosteric effectors alter regulation of the activity of glycogen synthase. When glycogen synthase is phosphorylated by glycogen synthase-phosphorylase kinase, it is rendered less active (glycogen synthaseb). When in this less active state, the enzyme activity can be enhanced by the positive allosteric effector glucose 6-phosphate. The more active form, glycogen synthase-a, does not respond to changing levels of glucose 6-phosphate.

An Increase in the Level of Glucose 6-Phosphate Is Expected