Which of the following events would be most likely to be observed following acute consumption of alcohol?

Question

Quizplus · Accepted Answer

Acute alcohol consumption leads to an increased NADH/NAD+ ratio, which inhibits gluconeogenesis and fatty acid oxidation, and promotes lactic acid production, leading to lactic acidosis.  The majority of the aberrant metabolic effects of ethanol intoxication stem from the actions of ADH and ALDH and the resultant cellular imbalance in the NADH:NAD+ ratio. Additionally, there is an increased rate of hepatic lactate production due to the effect of increased NADH on direction of the hepatic lactate dehydrogenase (LDH) reaction. This reversal of the LDH reaction in hepatocytes results in reduced capacity of the liver to divert lactate into glucose via gluconeogenesis. resulting in elevated lactate levels in the blood, leading to lactic acidosis.

Which of the Following Events Would Be Most Likely to Be