You are studying the effects of a novel compound in a variety of vascular and immune system assays. Your results demonstrate that the compound exhibits actitivies very similar to a previously identified eicosanoid. These activities include inhibition of platelet and leukocyte aggregation, induction of smooth muscle relaxation, decreased proliferation of T cells, decreased lymphocyte migration, and decreased secretion of IL-1a and IL-2. Which of the following eicosanoids exhibits biological activities most closely resembling those of your test compound?

Question

Quizplus · Accepted Answer

The Answer is D
EXPLANATION: Prostacyclin (PGI₂) is primarily synthesized by cardiac and vascular endothelial cells. Activities associated with this eicosanoid include inhibition of platelet and leukocyte aggregation, decreases in T-cell proliferation and lymphocyte migration and secretion of IL-1a and IL-2. Additional activities include smooth muscle relaxation leading to vasodilation.

You Are Studying the Effects of a Novel Compound in a Variety