You are studying the responses of renal tissue to
Ischemic injury in laboratory animals. You find
That in these animals there is an initial inflammatory response detectable within the renal tissue,
But it does not normally abate as expected; it only
Worsens resulting in total renal failure. Measurements of enzyme activities in renal tubule cells indicate that PLA₂ and COX-2 are functional. The lack of synthesis of which of the following lipid mediators is the most likely cause of the failure to limit the inflammatory responses in this animal model?

Question

Quizplus · Accepted Answer

The Answer of You are studying the responses of renal tissue to Ischemic injury in laboratory animals. You find That in these animals there is an initial inflammatory response detectable within the renal tissue, But it does not normally abate as expected; it only Worsens resulting in total renal failure. Measurements of enzyme activities in renal tubule cells indicate that PLA₂ and COX-2 are functional. The lack of synthesis of which of the following lipid mediators is the most likely cause of the failure to limit the inflammatory responses in this animal model?

You Are Studying the Responses of Renal Tissue to