Cholesterol is transported in the bloodstream in LDL, which bind to specific membrane receptors on the peripheral tissue cell membranes. The cholesterol then enters these cells by which of the following mechanisms?

Question

Quizplus · Accepted Answer

Cholesterol enters cells via endocytosis, where LDL binds to receptors and is internalized, then cholesterol is released in lysosomes.  The LDLs, formed as triglycerides, are removed from circulating VLDL. The liver takes up LDL after they have interacted with the LDL receptor to form a complex, which is endocytosed by the cell. For LDL receptors in the liver to recognize IDLs, they require the presence of both apoB-100 and apoE (the LDL receptor is also called the apoB-100/apoE receptor).

Cholesterol Is Transported in the Bloodstream in LDL, Which Bind