The initial reaction of the de novo synthesis pathway for pyrimidine nucleotides begins with glutamine and CO₂ and is complete with the formation of uridine monophosphate. Which of the following represents the rate-limiting enzyme in this pathway?

Question

Quizplus · Accepted Answer

Aspartate transcarbamoylase is the rate-limiting enzyme in the de novo synthesis pathway of pyrimidine nucleotides.

The Initial Reaction of the De Novo Synthesis Pathway for Pyrimidine