The migration of cancer cells from a solid tumor to another location in the body is referred to metastasis. This process requires the activity of which of the following enzymes?

Question

Quizplus · Accepted Answer

Matrix metalloproteinases (MMPs) are enzymes that degrade extracellular matrix components, facilitating cancer cell invasion and migration during metastasis.  Cell migration requires the hydrolysis of the extracellular matrix (ECM) holding the cells into a tissue or a tumor. The primary enzymes responsible for the degradation and remodeling of the ECM are the matrix metalloproteinases.

The Migration of Cancer Cells from a Solid Tumor to Another