All steroid hormone receptors share several structural similarities including the DNA-binding domain. The DNA-binding domain of the steroid hormones is known as which of the following?

Question

Quizplus · Accepted Answer

The DNA-binding domain of steroid hormone receptors is characterized by the presence of zinc finger motifs, which facilitate binding to specific DNA sequences.  The DNA-binding domain of steroid hormones consists of 2 nonrepetitive globular motifs where zinc is coordinated with 4 cysteine residues. This secondary and tertiary structure is distinct from that of the more classic zinc fingers which also include histidines in the coordination of the zinc atom. In the steroid hormone receptor the domain is called a type II zinc finger.

All Steroid Hormone Receptors Share Several Structural Similarities Including the DNA-Binding