Presentation of the platelet membrane protein complex, GPIIb-GPIIIa, which binds with von Willebrand factor, is necessary for which of the following?
A) activation of PKC leading to phosphorylation of myosin light chain and platelet morphology changes
B) cleavage and activation of high-molecularweight kininogen
C) inducing platelet cross-linking
D) release of thrombin from platelet granules
E) stimulation of endothelial and smooth muscle cell interaction resulting in vasoconstriction
Correct Answer:
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