How does self-assembly of microtubules occur? A)by helical twisting of strands of α-tubulin and β-tubulin B)by intermolecular interactions of dimers of α-tubulin and β-tubulin C)by polymerization of alternating α- and β-tubulin into a repeating α-β-α-β-.strand D)by inter-subunit interaction to form α₂β₂-tetramers of tubulin

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Quizplus · Accepted Answer

Microtubules are formed by the self-assembly of dimers of α-tubulin and β-tubulin, which interact through non-covalent interactions such as hydrogen bonding, van der Waals forces, and electrostatic interactions to form linear protofilaments. The protofilaments further interact with each other through lateral contacts to form a hollow, cylindrical structure known as a microtubule.

How Does Self-Assembly of Microtubules Occur