Which of the following does NOT occur during kinesin movement along a microtubule?
A)Leading head binds a new site on tubulin,with ADP dissociation.
B)The kinesin head with ADP is bound to tubulin,and the kinesin head with ATP is ready to move ahead.
C)Conformational changes in the neck linkers flip the trailing head to the next tubulin binding site.
D)ADP and Pi dissociate and ATP binds leading head.

Question

Quizplus · Accepted Answer

Kinesin movement along a microtubule involves a cycle where the leading head binds a new site on the microtubule with ADP dissociation, followed by ATP binding which causes conformational changes. These changes flip the trailing head forward. The statement in B is incorrect because it suggests a simultaneous presence of ADP and ATP in a way that does not align with the known cycle of kinesin movement. In the correct cycle, after the leading head binds to the microtubule, ADP is released, and then ATP binds, which triggers the movement.

Which of the Following Does NOT Occur During Kinesin Movement