Which of the following does NOT occur in the malate-aspartate shuttle?
A)OAA is transaminated to aspartate.
B)OAA is reduced to malate.
C)Malate is oxidized to OAA.
D)Aspartate is translocated to the matrix.

Question

Quizplus · Accepted Answer

In the malate-aspartate shuttle, aspartate is transaminated to OAA and then converted to malate, which is transported into the mitochondrial matrix. Once inside the matrix, malate is oxidized back to OAA and the process starts over again. However, aspartate is not transported into the matrix; rather, it is transaminated to OAA in the mitochondrial intermembrane space. Therefore, choice D is the correct answer as it incorrectly states that aspartate is translocated to the matrix.

Which of the Following Does NOT Occur in the Malate-Aspartate