The base-pair edges in the major groove act as a recognition matrix.How are they identifiable?
A)through van der Waals interactions with specific proteins
B)through hydrophobic interactions with specific proteins
C)through H-bonding with specific proteins
D)through ionic binding interactions with specific proteins

Question

Quizplus · Accepted Answer

The base-pair edges in the major groove are identifiable through H-bonding interactions with specific proteins that recognize and bind to specific DNA sequences. These interactions involve the formation of specific H-bonds between amino acid residues in the protein and the nitrogenous bases in the DNA, allowing for a high degree of specificity in DNA-protein interactions. Van der Waals, hydrophobic, and ionic interactions can also contribute to DNA-protein recognition, but H-bonding is the most specific and critical type of interaction.

The Base-Pair Edges in the Major Groove Act as a Recognition