Antiepileptic drug, leads to tolerance to drug ,after 2-3 weeks it will not activate its metabolism and it is needed to increase the dose and ultimately inhibits the hepatic microsomal enzymes.

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Carbamazepine is an antiepileptic drug that induces its own metabolism (autoinduction), leading to tolerance and the need for dose adjustment. It initially increases hepatic enzyme activity but can eventually inhibit them.

Antiepileptic Drug, Leads to Tolerance to Drug ,After 2-3 Weeks