As a result of leukocyte adhesion deficiency, white blood cells cannot:
A) Present antigen
B) Release granules
C) Perform diapedesis
D) Phagocytose pathogens

Question

Quizplus · Accepted Answer

Adhesion molecules are important for adherence of leukocytes to the surface of endothelial cells during diapedesis. This process allows the cells to leave the circulation and travel to the site of infection. Patients with leukocyte adhesion deficiency do not express these surface molecules on their immune cells, so their white blood cells cannot migrate to the site of infection to aid in elimination of pathogens. The adhesion molecules that are defective in leukocyte adhesion deficiency are not involved in antigen presentation, granule release, or phagocytosis.

As a Result of Leukocyte Adhesion Deficiency, White Blood Cells