Severe combined immunodeficiency is most commonly caused by
A) chromosome 22 trisomy.
B) Y-linked inherited hypermetabolism.
C) X-linked inherited enzyme or receptor deficiency.
D) chromosome 7 deletion.
E) XXY inheritance.

Question

Quizplus · Accepted Answer

Severe combined immunodeficiency (SCID) is most commonly caused by X-linked inherited enzyme or receptor deficiencies, particularly in genes that encode for the common cytokine receptor gamma chain (γc) or adenosine deaminase (ADA).

Severe Combined Immunodeficiency Is Most Commonly Caused by